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    Bruker AvanceCore

    AvanceCore – NMR Spectrometer

    Bruker AvanceCore is a high-resolution 400 MHz NMR spectrometer that delivers the quality and performance of professional NMR systems at a more accessible cost. It is designed for laboratories requiring reliable and versatile NMR analysis, combined with ease of use and optimized operating costs.

    AvanceCore enables molecular structure determination and confirmation, compound identification and quantification, mixture analysis, and investigation of molecular interactions. It supports advanced 1D and 2D NMR experiments, including COSY, TOCSY, ROESY, NOESY, DOSY, HSQC, and HMBC.

    Category:

    CONFIGURATIONS

    ADVANTAGES

    APPLICATIONS

    TECHNICAL SPECIFICATIONS

    Configurations

    AvanceCore is available in three predefined configurations:

    AvanceCore Foundation

    The entry-level configuration for high-resolution ¹H NMR spectroscopy. It includes a 400 MHz NMR magnet, console, and 5 mm probe.

    AvanceCore Select

    An advanced configuration supporting ¹H and heteronuclear experiments, including ¹³C and ³¹P.

    AvanceCore Convenience

    A configuration designed for automated routine operation and multi-user environments. It includes a 24-position sample changer, expandable to 60 positions, as well as IconNMR software for automated measurements.

    The system can be upgraded from Foundation to Select, and from Select to Convenience, allowing the system to grow with the laboratory’s requirements.

    Advantages

    • High-resolution 400 MHz NMR
    • Two RF channels
    • High resolution and signal-to-noise ratio
    • High performance at an accessible cost
    • Flexible activation of additional functions through software licenses
    • Suitable for compound identification and quantification
    • Efficient analysis of mixtures and trace impurities
    • Support for advanced 1D and 2D NMR experiments
    • Automated routine measurement capabilities
    • Upgradeable configuration to meet evolving laboratory requirements
    • Simple sample preparation and fully automated measurement options

    Applications

    AvanceCore is suitable for:

    • Molecular structure determination and confirmation
    • Compound identification and quantification
    • Mixture and impurity analysis
    • Investigation of molecular interactions
    • Pharmaceutical research and drug development
    • Chemical research
    • Natural product analysis
    • Quality control
    • Routine laboratory analysis
    • Research and development in the chemical and pharmaceutical industries

    Technical Specifications

    • NMR frequency: 400 MHz
    • RF channels: 2
    • Time resolution: 12.5 ns
    • Frequency resolution: < 0.005 Hz
    • Digital lock: Included
    • RF amplifier range: ⁵⁷Fe–¹⁹F/¹H
    • NMR tube diameter: 5 mm
    • Probe channels: ¹H, ¹⁹F, BB, and ²H Lock
    • Z-gradient: 50 G/cm
    • Typical helium hold time: 365 days
    • Typical nitrogen hold time: 16 days
    • Accessories: Sample temperature control unit and 24-position sample changer, expandable to 60 positions
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