chemReactor CR

Büchiglas chemReactor CR — High-Performance Reactor System

Büchiglas chemReactor CR is a versatile reactor system designed for chemical process development, process scale-up, and kilogram-scale production, as well as pilot plant applications. It is particularly suitable for API synthesis and cGMP production in batch and semi-batch processes.

Category:

Reactor systems 5 - 250 liter

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For more information, please visit the manufacturer’s website

ADVANTAGES

APPLICATIONS

TECHNICAL SPECIFICATIONS

Advantages

Reactor volumes from 15, 30, 60, 100, 160, and 250 L
Combination of borosilicate glass 3.3 and glass-lined steel
Excellent heat transfer and stable control of process conditions
Enables visual monitoring of chemical reactions
Full vacuum operation
ATEX version available for safe operation with solvents and acids
Suitable for cGMP processes
CIP cleaning capability
Process automation and customization options available

Applications

Chemical synthesis
Peptide production
API production
Extraction and evaporation
Process development and optimization
Purification and crystallization
Cryogenic reactions
Separation
Process scale-up
Pilot plant and kilo-lab applications

Technical Specifications

Reactor volume: 15, 30, 60, 100, 160, and 250 L
Temperature range: −60 °C to +200 °C
Optional temperature range: down to −90 °C
Operating pressure: −1.0 bar (full vacuum) to +0.5 bar
Materials: borosilicate glass 3.3, glass-lined steel, PTFE, PFA, and tantalum
Versions/standards: ATEX Zone 1 (0), CE, cGMP
Additional options: reactor lifting system, sampling device, pH monitoring and control, gas supply, vacuum/exhaust lines, additional dosing and receiving vessels, cryogenic vessel, and various process automation configurations