Peptide Synthesizers
Büchiglas Peptide Synthesizers are designed for Solid Phase Peptide Synthesis (SPPS), from laboratory and pilot-scale applications to commercial production. Standard and fully customized solutions are available for volumes from 5 to 500 L, with options for manual or fully automated operation. All systems are designed to meet cGMP requirements and are suitable for the production of high-quality peptide APIs.
Category:
ADVANTAGES
APPLICATIONS
TECHNICAL SPECIFICATIONS
Advantages
- Volumes from 5 to 500 L
- Solutions for manual and fully automated synthesis
- High reproducibility and consistent results
- cGMP compliance and ATEX certification
- Precise temperature control during the process
- Efficient mixing of resin, solvents, and reagents
- Simple and efficient filtration
- Customizable according to specific process requirements
- Automated dosing of solvents and reagents
- Real-time monitoring of key process parameters
Applications
- Solid Phase Peptide Synthesis (SPPS)
- Peptide synthesis
- Process development
- Pilot and kilo-lab production
- Commercial peptide production
- Peptide API production
- cGMP manufacturing processes
Technical Specifications
- Volume: 5–500 L
- Operating pressure: −1.0 bar (full vacuum) to +0.5 bar
- Temperature range: −60 °C to +150 °C, or up to +200 °C
- Agitation: Multi-stage mechanical agitator with adjustable height
- Filtration: Tilting filter plate for efficient filtration and easy filter cloth replacement
- Automation: Gravimetric or volumetric dosing, automatic pumps, and monitoring of temperature, pH, time, volume, and weight
- Materials: Chemically resistant materials suitable for repeated SPPS cycles
- Versions: Manual and fully automated systems