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    chemReactor GR

    Büchiglas chemReactor GR — Glass Pilot Reactor System

    Büchiglas chemReactor GR is a versatile glass reactor system designed for chemical process development, process simulation, scale-up, and kilogram-scale production. It is suitable for batch and semi-batch processes, as well as cGMP production of API substances.

    ADVANTAGES

    APPLICATIONS

    TECHNICAL SPECIFICATIONS

    Advantages

    • Reactor volumes of 15, 30, and 60 L
    • Fully glass reactor with a jacket and visual monitoring of the reaction
    • Versatile glass distillation system
    • Full vacuum operation
    • High chemical resistance and inert materials
    • ATEX version available for safe operation with solvents and acids
    • Suitable for cGMP processes
    • CIP cleaning capability
    • Modular configuration with options for process-specific customization
    • Integration of additional equipment for temperature control, filtration, monitoring, and process automation

    Applications

    • Chemical synthesis
    • Peptide production
    • Extraction and evaporation
    • Process development and optimization
    • Purification and crystallization
    • Cryogenic reactions
    • Separation
    • Process scale-up
    • API production
    • Pilot plant and kilo-lab applications

    Technical Specifications

    • Reactor volume: 15, 30, and 60 L
    • Temperature range: −60 °C to +200 °C
    • Optional temperature range: down to −90 °C
    • Operating pressure: −1.0 bar (full vacuum) to +0.5 bar
    • Materials: borosilicate glass 3.3, glass-lined steel, PTFE, PFA, and tantalum
    • Versions/standards: ATEX Zone 1 (0), CE, cGMP, FDA
    • Additional options: reactor lifting system, triple jacket, sampling system, pH monitoring and control, gas supply, vacuum/exhaust lines, additional dosing and receiving vessels, and solid dosing system
    • Distillation system: condensers, receiving vessel, distillation column, and Dean-Stark phase separator
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